Nutrition value, anti-obesity and anti-inflammatory effects of mangoesteen fruit

Health Science and Practical Remedies

The purple mangoesteen (Garcinia mangostana) is a tropical evergreen tree and native to Sunda Islands and the Moluccas of Indonesia. It grows mainly in Southeast Asia and tropical South American countries. The white flesh part of purple mangoesteen fruit is edible.

Healthy benefits of mangoesteen:
  1. Mangoesteen showed weight loss and anti-obesity effects in human clinical studies.
  2. Mangoseteen can be used for obesity, skin problems, wounds, dysentery, urinary tract infections, abdominal pain, diarrhea, suppuration and chronic ulcers.
  3. The crude ethanol extract of mangosteen pericarp (Garcinia mangostana) showed strong anti-skin cancer effect in two skin cancer cell lines, with potential as an anti-skin cancer agent. Skin cancer are often resistant to conventional chemotherapy.
  4. Mangoesteen fruits are getting popular as drinks, nutritional supplement ingredient and functional foods.
Pharmacological properties of mangoesteen: Anti-tumor, anti-ulcer, anti-allergy, anti-inflammatory, antibacterial, antiviral, antioxidant and reduces blood levels of C-reactive protein (biomarker of inflammation).

Bio-active compounds in mangoesteen fruits:
  • Gartanin (CAS Number: 33390-42-0) shows anti-ulcer property.
  • 8-Deoxygartanin (CAS Number: 33390-41-9) is a platelet aggregation inhibitor, anti-ulcer and cytotoxic agent, also inhibits HIV protease.
  • Normangostin (CAS Number: 31271-07-5) inhibits HIV protease and shows anti-ulcer property.
  • Garcinone E (CAS Number: 112649-21-5) is a cytotoxic agent.
Nutritional value                         per 100 g (3.5 oz)
  • Energy                                     305 kJ (73 kcal)
  • Carbohydrates                               17.91 g
  • Dietary fiber                                  1.8 g
  • Fat                                                 0.58 g
  • Protein                                           0.41 g
  • Thiamine (vitamin B1)               0.054 mg (5%)
  • Riboflavin (vitamin B2)             0.054 mg (5%)
  • Niacin (vitamin B3)                   0.286 mg (2%)
  • Pantothenic acid (B5)                 0.032 mg (1%)
  • Vitamin B6                                 0.018 mg (1%)
  • Folate (vit. B9)                           31 μg (8%)
  • Vitamin C                                   2.9 mg (3%)
  • Calcium                                       12 mg (1%)
  • Iron                                              0.3 mg (2%)
  • Magnesium                                 13 mg (4%)
  • Manganese                                  0.102 mg (5%)
  • Phosphorus                                  8 mg (1%)
  • Potassium                                   48 mg (1%)
  • Sodium                                       7 mg (0%)
  • Zinc                                           0.21 mg (2%)   (USDA Database)
Phytother Res., 2009, Aug; 23(8):1047-65
Food Chem Toxicol. 2008, Oct; 46(10): 3227-39
Phytochemistry, 1982, 21:117–9
Journal of Agricultural and Food Chemistry, 2006, 54 (6): 2077–82
Phytotherapy Research, 2009, 23 (8): 1047–65
Food Chem Toxicol. 2012 Sep; 50(9): 3004-13

Dr. Jeff Zhao (赵吉福), a natural product scientist, has been studying active ingredients, new drugs, cosmetics and  nutritional supplements for over 35 years.

Warning: The information in this web site is for your information only. You should not use our information to diagnose or treat any health problems or illnesses without consulting your medical doctors.​​​​


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